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Drugs that inhibit CYP2D6 action, such as paroxetine and quinidine, might result in reduced clearance of oxycodone which may lead to an increase in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in a rise in oxycodone Cmax by eleven%, AUC by 13%, and t½ elim.Clients needs to be titrated to suffering aid Except unm

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